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HSC division upon aging
 

HSC division upon aging

Ageing of haematopoietic stem cells (HSCs) is associated with impaired haematopoiesis in the elderly. Despite a large amount of data describing the decline of HSC function upon ageing, the molecular mechanisms of this process remain still largely unknown, which precludes rational approaches to attenuate stem cell ageing.
Analysis of mode and outcome of LT-HSCs division upon aging: symmetric and asymmetric division.
  Geiger Laboratory
 
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