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Mesenchymal stem cells and the HSC niche
 

Mesenchymal stem cells and the HSC niche

Among others mesenchymal stem cells (MSCs) and mesenchymal derived cell types form the hematopoietic stem cell (HSC) niches and age-related alterations of the MSCs and mesenchymal lineages influence the HSC niche and consequently the HSCs. The project focuses on two essential mesenchymal-derived HSC niche constituents and their influences and affects on HSCs: the perivascular Nestin-positive MSCs and the endosteal osteoblasts.
  Geiger Laboratory
 
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