Welcome to the geigerlab
Our Lab is interested in stem cells, especially hematopoietic and intestinal stem cells and aging of stem cells. We work on unraveling intrinsic changes in stem cells upon aging as well as how the niche is affecting stem cell behaviour. Furthermore, we investigate the involvement of hematopoietic stem cells (HSCs) in an aging immune system and the causes and consequences of HSC transformation. Another main topic of our research is how clonality and heterogeneity are achieved in stem cells.
News from the Lab
Congratulations Dr. Mona Vogel !
Mona defended her PhD thesis "summa cum laude" and at the same day received a ProTrainU grant from Ulm University.
Double Congratulations !
Ulm University awarded five young researchers start-up funding and presented their scientific work. Dr. Hanna Leins is investigating the relationship between the microbiome and the immune system.
At the annual meeting of the German society for aging research our Post-Doc Mehmet received the Fritz Boege Prize for Innovation for his poster: "Hematopoietic stem cells in perisinusoidal niches are protected from aging".
A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells.
Tiwari RL, Mishra P, Martin N, George NO, Sakk V, Soller K, Nalapareddy K, Nattamai K, Scharffetter-Kochanek K, Florian MC, Geiger H.
Aging (Albany NY). 2021 Feb 25
Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity.
Amoah A, Keller A, Emini R, Hoenicka M, Liebold A, Vollmer A, Eiwen K, Soller K, Sakk V, Zheng Y, Florian MC, Geiger H.
Haematologica. 2021 Jan 14
Florian MC, Leins H, Gobs M, Han Y, Marka G, Soller K, Vollmer A, Sakk V, Nattamai KJ, Rayes A, Zhao X, Setchell K, Mulaw M, Wagner W, Zheng Y, Geiger H.
Aging Cell. 2020 Aug